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Studies have reported additive benefits in glycemic control, body weight reduction, and blood pressure lowering without major unexpected safety signals [40,41,42,43]

Nevertheless, recent advances in understanding the molecular mechanisms, regulatory factors of GLP-1 secretion, signaling pathways, and transcription factors that are effective in endocrine cell differentiation may pave the way for the development of effective applicable medications that can increase GLP-1 secretion and improve L-cell differentiation

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Wegovy also has an FDA approval for cardiovascular risk reduction (March 2024), which makes it attractive for coverage